Bacterial Adaptation & Response Networks

Smit Lab:

John Smit

Lab Webpage

Our main research focus is directed to study of a regularly structured surface (S) layer and the biotechnology applications that derive from our understanding of this structure. The Caulobacter S-layer is a two-dimensional crystalline array on the cell’s surface composed of a single secreted protein. The S-layer probably helps Caulobacters fend off pathogenic bacteria, viruses and lytic enzymes.  It appears to be important to cover the entire cell at all times and so this is the most abundant protein of the cell.  We analyze the S-layer genetically and biochemically to understand the high level secretion apparatus, as well as to learn how the S-layer self-assembles and remains surface attached.

a place of mind, The University of British Columbia

Bacterial Adaptation & Response Networks
2350 Health Sciences Mall,
Vancouver, BC, V6T 1Z3, Canada

Emergency Procedures | Accessibility | Contact UBC  | © Copyright The University of British Columbia